HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression

HIC1 (Hypermethylated In Cancer 1) a tumor suppressor gene located at 17p13.3, is frequently deleted or epigenetically silenced in many human tumors. HIC1 encodes a transcriptional repressor involved in various aspects of the DNA damage response and in complex regulatory loops with P53 and SIRT1. HI...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dubuissez, Marion, Paget, Sonia, Abdelfettah, Souhila, Spruyt, Nathalie, Dehennaut, Vanessa, Boulay, Gaylor, Loison, Ingrid, de Schutter, Clementine, Rood, Brian R., Duterque-Coquillaud, Martine, Leroy, Xavier, Leprince, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665237/
https://ncbi.nlm.nih.gov/pubmed/33227080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27786
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