Characterization of the ExoU activation mechanism using EPR and integrative modeling

ExoU, a type III secreted phospholipase effector of Pseudomonas aeruginosa, serves as a prototype to model large, dynamic, membrane-associated proteins. ExoU is synergistically activated by interactions with membrane lipids and ubiquitin. To dissect the activation mechanism, structural homology was...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Tessmer, Maxx H., DeCero, Samuel A., del Alamo, Diego, Riegert, Molly O., Meiler, Jens, Frank, Dara W., Feix, Jimmy B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665212/
https://ncbi.nlm.nih.gov/pubmed/33184362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76023-3
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk