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Cooperative Substrate-Cofactor Interactions and Membrane Localization of the Bacterial Phospholipase A(2) (PLA(2)) Enzyme, ExoU
The ExoU type III secretion enzyme is a potent phospholipase A(2) secreted by the Gram-negative opportunistic pathogen, Pseudomonas aeruginosa. Activation of phospholipase activity is induced by protein-protein interactions with ubiquitin in the cytosol of a targeted eukaryotic cell, leading to dest...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5336173/ https://ncbi.nlm.nih.gov/pubmed/28069812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.760074 |
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