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Characterization of Phospholipase Activity of the Pseudomonas aeruginosa Type III Cytotoxin, ExoU

Recombinant ExoU (rExoU) and yeast extract were used to optimize an in vitro phospholipase assay as a basis for identifying the mechanism for enzyme activation and substrate specificity. Our results support a model in which a eukaryotic protein cofactor or complex facilitates the interaction of rExo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sato, Hiromi, Feix, Jimmy B., Hillard, Cecilia J., Frank, Dara W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC545705/
https://ncbi.nlm.nih.gov/pubmed/15659695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.3.1192-1195.2005
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