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Polymeric persulfide prodrugs: Mitigating oxidative stress through controlled delivery of reactive sulfur species

Related biologically to the known gasotransmitter hydrogen sulfide (H(2)S), persulfides (R–SSH) have recently been recognized as native signaling compounds and redox regulators in their own right. Reported here is the synthesis, characterization, and in vitro evaluation of a small molecule persulfid...

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Vydáno v:ACS Macro Lett
Hlavní autoři: Dillon, Kearsley M., Carrazzone, Ryan J., Wang, Yin, Powell, Chadwick R., Matson, John B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665160/
https://ncbi.nlm.nih.gov/pubmed/33194315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmacrolett.0c00118
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