In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors

Epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2) are crucial targetable enzymes in cancer management. Therefore, herein, new 2-[(5-((1H-indol-3-yl)methyl)-1,3,4-oxadiazol-2-yl)thio]-N-(thiazol/benzothiazol-2-yl)acetamides (2a–i) were designed and synthesized as EGFR and COX-2 inh...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Sever, Belgin, Altıntop, Mehlika Dilek, Özdemir, Ahmet, Akalın Çiftçi, Gülşen, Ellakwa, Doha E., Tateishi, Hiroshi, Radwan, Mohamed O., Ibrahim, Mahmoud A. A., Otsuka, Masami, Fujita, Mikako, Ciftci, Halil I., Ali, Taha F. S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664637/
https://ncbi.nlm.nih.gov/pubmed/33171861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25215190
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia