ロード中...

In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors

Epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2) are crucial targetable enzymes in cancer management. Therefore, herein, new 2-[(5-((1H-indol-3-yl)methyl)-1,3,4-oxadiazol-2-yl)thio]-N-(thiazol/benzothiazol-2-yl)acetamides (2a–i) were designed and synthesized as EGFR and COX-2 inh...

詳細記述

保存先:
書誌詳細
出版年:Molecules
主要な著者: Sever, Belgin, Altıntop, Mehlika Dilek, Özdemir, Ahmet, Akalın Çiftçi, Gülşen, Ellakwa, Doha E., Tateishi, Hiroshi, Radwan, Mohamed O., Ibrahim, Mahmoud A. A., Otsuka, Masami, Fujita, Mikako, Ciftci, Halil I., Ali, Taha F. S.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664637/
https://ncbi.nlm.nih.gov/pubmed/33171861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25215190
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!