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Comprehensive Study on Thiadiazole-Based Anticancer Agents Inducing Cell Cycle Arrest and Apoptosis/Necrosis Through Suppression of Akt Activity in Lung Adenocarcinoma and Glioma Cells

OBJECTIVES: Akt is considered as an attractive target for anticancer drug discovery and development and therefore extensive efforts have been devoted to the discovery of new potent anticancer agents targeting Akt. MATERIALS AND METHODS: Due to the importance of thiadiazoles for anticancer drug disco...

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Detalhes bibliográficos
Publicado no:Turk J Pharm Sci
Main Authors: AKALIN ÇİFTÇİ, Gülşen, SEVER, Belgin, ALTINTOP, Mehlika Dilek
Formato: Artigo
Idioma:Inglês
Publicado em: Galenos Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227970/
https://ncbi.nlm.nih.gov/pubmed/32454705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjps.galenos.2019.2018.96658
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