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Comprehensive Study on Thiadiazole-Based Anticancer Agents Inducing Cell Cycle Arrest and Apoptosis/Necrosis Through Suppression of Akt Activity in Lung Adenocarcinoma and Glioma Cells

OBJECTIVES: Akt is considered as an attractive target for anticancer drug discovery and development and therefore extensive efforts have been devoted to the discovery of new potent anticancer agents targeting Akt. MATERIALS AND METHODS: Due to the importance of thiadiazoles for anticancer drug disco...

詳細記述

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書誌詳細
出版年:Turk J Pharm Sci
主要な著者: AKALIN ÇİFTÇİ, Gülşen, SEVER, Belgin, ALTINTOP, Mehlika Dilek
フォーマット: Artigo
言語:Inglês
出版事項: Galenos Publishing 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227970/
https://ncbi.nlm.nih.gov/pubmed/32454705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjps.galenos.2019.2018.96658
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