Targeting foam cell formation in inflammatory brain diseases by the histone modifier MS‐275

OBJECTIVE: To assess class I‐histone deacetylase (HDAC) inhibition on formation of lipid‐accumulating, disease‐promoting phagocytes upon myelin load in vitro, relevant for neuroinflammatory disorders like multiple sclerosis (MS) and cerebral X‐linked adrenoleukodystrophy (X‐ALD). METHODS: Immunohist...

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Bibliografiske detaljer
Udgivet i:Ann Clin Transl Neurol
Main Authors: Zierfuss, Bettina, Weinhofer, Isabelle, Buda, Agnieszka, Popitsch, Niko, Hess, Lena, Moos, Verena, Hametner, Simon, Kemp, Stephan, Köhler, Wolfgang, Forss‐Petter, Sonja, Seiser, Christian, Berger, Johannes
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664285/
https://ncbi.nlm.nih.gov/pubmed/32997393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51200
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