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Molecular Mechanisms Underlying Muscle Wasting in Huntington’s Disease
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by pathogenic expansions of the triplet cytosine-adenosine-guanosine (CAG) within the Huntingtin gene. These expansions lead to a prolongation of the poly-glutamine stretch at the N-terminus of Huntingtin causing pr...
Gardado en:
| Publicado en: | Int J Mol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7664236/ https://ncbi.nlm.nih.gov/pubmed/33167595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218314 |
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