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Huntington’s disease: underlying molecular mechanisms and emerging concepts

Huntington’s disease (HD) is a progressive neurodegenerative disorder for which no disease modifying treatments exist. Many molecular changes and cellular consequences that underlie HD are observed in other neurological disorders suggesting that common pathological mechanisms and pathways may exist....

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Detalhes bibliográficos
Main Authors: Labbadia, John, Morimoto, Richard I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955166/
https://ncbi.nlm.nih.gov/pubmed/23768628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2013.05.003
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