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Histone H3K9 Demethylase JMJD2B Plays a Role in LXRα-Dependent Lipogenesis
Ligand-activated liver X receptor α (LXRα) upregulates the expression of hepatic lipogenic genes, which leads to triglyceride (TG) accumulation, resulting in nonalcoholic fatty liver disease (NAFLD). Thus, LXRα regulation may provide a novel therapeutic target against NAFLD. However, histone methyla...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7664202/ https://ncbi.nlm.nih.gov/pubmed/33167594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218313 |
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