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Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2

Understanding the epigenetic mechanisms underlying the progression of hepatic steatosis is important for identifying new therapeutic targets against nonalcoholic fatty liver disease (NAFLD). We investigated the functional role of histone demethylase JMJD2B in the pathologic regulation of hepatic ste...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Ji-Hyun, Jung, Dae Young, Nagappan, Arulkumar, Jung, Myeong Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137221/
https://ncbi.nlm.nih.gov/pubmed/30214048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31953-x
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