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Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2

Understanding the epigenetic mechanisms underlying the progression of hepatic steatosis is important for identifying new therapeutic targets against nonalcoholic fatty liver disease (NAFLD). We investigated the functional role of histone demethylase JMJD2B in the pathologic regulation of hepatic ste...

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書目詳細資料
發表在:Sci Rep
Main Authors: Kim, Ji-Hyun, Jung, Dae Young, Nagappan, Arulkumar, Jung, Myeong Ho
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137221/
https://ncbi.nlm.nih.gov/pubmed/30214048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31953-x
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