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Chitosan Oligosaccharides Suppress Nuclear Factor-Kappa B Activation and Ameliorate Experimental Autoimmune Uveoretinitis in Mice

We investigated the therapeutic potential and mechanism of chitosan oligosaccharides (COS) for experimental autoimmune uveoretinitis (EAU) in mice. EAU was induced in C57/BL6 mice by injection of human interphotoreceptor retinoid-binding protein (IRBP) peptides. At the same time, a high or low dose...

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Publicat a:Int J Mol Sci
Autors principals: Hsu, Sheng-Min, Yang, Chang-Hao, Tsai, Hsien-Yang, Lin, Chia-Jhen, Fang, Yi-Hsuan, Shieh, Chi-Chang, Chen, Shun-Hua
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664198/
https://ncbi.nlm.nih.gov/pubmed/33171990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218326
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