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Chitosan Oligosaccharides Suppress Nuclear Factor-Kappa B Activation and Ameliorate Experimental Autoimmune Uveoretinitis in Mice

We investigated the therapeutic potential and mechanism of chitosan oligosaccharides (COS) for experimental autoimmune uveoretinitis (EAU) in mice. EAU was induced in C57/BL6 mice by injection of human interphotoreceptor retinoid-binding protein (IRBP) peptides. At the same time, a high or low dose...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hsu, Sheng-Min, Yang, Chang-Hao, Tsai, Hsien-Yang, Lin, Chia-Jhen, Fang, Yi-Hsuan, Shieh, Chi-Chang, Chen, Shun-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664198/
https://ncbi.nlm.nih.gov/pubmed/33171990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218326
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