Proteasome Inhibitor Bortezomib Suppresses Nuclear Factor-Kappa B Activation and Ameliorates Eye Inflammation in Experimental Autoimmune Uveitis

Bortezomib is a proteasome inhibitor used for hematologic cancer treatment. Since it can suppress NF-κB activation, which is critical for the inflammatory process, bortezomib has been found to possess anti-inflammatory activity. In this study, we evaluated the effect of bortezomib on experimental au...

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Dettagli Bibliografici
Pubblicato in:Mediators Inflamm
Autori principali: Hsu, Sheng-Min, Yang, Chang-Hao, Shen, Fang-Hsiu, Chen, Shun-Hua, Lin, Chia-Jhen, Shieh, Chi-Chang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306382/
https://ncbi.nlm.nih.gov/pubmed/25653480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/847373
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