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The HGF/Met/NF-κB Pathway Regulates RANKL Expression in Osteoblasts and Bone Marrow Stromal Cells

Multiple myeloma (MM)-induced bone disease occurs through hyperactivation of osteoclasts by several factors secreted by MM cells. MM cell-secreted factors induce osteoclast differentiation and activation via direct and indirect actions including enhanced expression of receptor activator of nuclear f...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Tsubaki, Masanobu, Seki, Shiori, Takeda, Tomoya, Chihara, Akiko, Arai, Yuuko, Morii, Yuusuke, Imano, Motohiro, Satou, Takao, Shimomura, Kazunori, Nishida, Shozo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663721/
https://ncbi.nlm.nih.gov/pubmed/33114380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217905
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