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Enhanced Dopamine Transmission and Hyperactivity in the Dopamine Transporter Heterozygous Mice Lacking the D3 Dopamine Receptor

Dopamine transporter knockout (DATk) mice are known to demonstrate profound hyperactivity concurrent with elevated (5-fold) extracellular dopamine in the basal ganglia. At the same time, heterozygous DAT mice (DATh) demonstrate a 2-fold increase in dopamine levels yet only a marginal elevation in lo...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Sotnikova, Tatyana D., Efimova, Evgeniya V., Gainetdinov, Raul R.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662256/
https://ncbi.nlm.nih.gov/pubmed/33153031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218216
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