Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter

The dopamine transporter (DAT) plays a key role in the regulation of dopaminergic signaling wherein it controls both the spatial and temporal actions of dopamine. Here we evaluated the behavioral and neurochemical consequences of increased DAT function by generating DAT transgenic mice (DAT-tg) that...

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Hauptverfasser: Salahpour, Ali, Ramsey, Amy J., Medvedev, Ivan O., Kile, Brian, Sotnikova, Tatyana D., Holmstrand, Ericka, Ghisi, Valentina, Nicholls, Peter J., Wong, Ling, Murphy, Karen, Sesack, Susan R., Wightman, R. Mark, Gainetdinov, Raul R., Caron, Marc G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393812/
https://ncbi.nlm.nih.gov/pubmed/18347339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707646105
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