Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter

The dopamine transporter (DAT) plays a key role in the regulation of dopaminergic signaling wherein it controls both the spatial and temporal actions of dopamine. Here we evaluated the behavioral and neurochemical consequences of increased DAT function by generating DAT transgenic mice (DAT-tg) that...

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Detalhes bibliográficos
Main Authors: Salahpour, Ali, Ramsey, Amy J., Medvedev, Ivan O., Kile, Brian, Sotnikova, Tatyana D., Holmstrand, Ericka, Ghisi, Valentina, Nicholls, Peter J., Wong, Ling, Murphy, Karen, Sesack, Susan R., Wightman, R. Mark, Gainetdinov, Raul R., Caron, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393812/
https://ncbi.nlm.nih.gov/pubmed/18347339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707646105
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