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Developmental and Functional Hair Cell-Like Cells Induced by Atoh1 Overexpression in the Adult Mammalian Cochlea In Vitro

Hair cells (HCs) in the mammalian cochleae cannot spontaneously regenerate once damaged, resulting in permanent hearing loss. It has been shown that Atoh1 overexpression induces hair cell-like cells (HCLCs) in the cochlea of newborn rodents, but this is hard to achieve in adult mammals. In this stud...

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Publicado en:Neural Plast
Autores principales: Kong, Lingyi, Xin, Yuan, Chi, Fanglu, Chen, Jie, Yang, Juanmei
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7661126/
https://ncbi.nlm.nih.gov/pubmed/33204251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8885813
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