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Developmental and Functional Hair Cell-Like Cells Induced by Atoh1 Overexpression in the Adult Mammalian Cochlea In Vitro

Hair cells (HCs) in the mammalian cochleae cannot spontaneously regenerate once damaged, resulting in permanent hearing loss. It has been shown that Atoh1 overexpression induces hair cell-like cells (HCLCs) in the cochlea of newborn rodents, but this is hard to achieve in adult mammals. In this stud...

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Detalhes bibliográficos
Publicado no:Neural Plast
Main Authors: Kong, Lingyi, Xin, Yuan, Chi, Fanglu, Chen, Jie, Yang, Juanmei
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7661126/
https://ncbi.nlm.nih.gov/pubmed/33204251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8885813
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