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Polycyclizations of Ketoesters: Synthesis of Complex Tricycles with up to Five Stereogenic Centers from Available Starting Materials

[Image: see text] Here we present a polycyclization of oxotriphenylhexanoates. The polycyclization is governed by electronic effects, and three major synthetic paths have been established leading to stereochemically complex tricyclic frameworks with up to five stereogenic centers. The method is comp...

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Publicat a:Org Lett
Autors principals: Kamlar, Martin, Runemark, August, Císařová, Ivana, Sundén, Henrik
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660947/
https://ncbi.nlm.nih.gov/pubmed/33079554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c03020
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