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Polycyclizations of Ketoesters: Synthesis of Complex Tricycles with up to Five Stereogenic Centers from Available Starting Materials

[Image: see text] Here we present a polycyclization of oxotriphenylhexanoates. The polycyclization is governed by electronic effects, and three major synthetic paths have been established leading to stereochemically complex tricyclic frameworks with up to five stereogenic centers. The method is comp...

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Publicado en:Org Lett
Main Authors: Kamlar, Martin, Runemark, August, Císařová, Ivana, Sundén, Henrik
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660947/
https://ncbi.nlm.nih.gov/pubmed/33079554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c03020
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