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Learning and interpreting the gene regulatory grammar in a deep learning framework

Deep neural networks (DNNs) have achieved state-of-the-art performance in identifying gene regulatory sequences, but they have provided limited insight into the biology of regulatory elements due to the difficulty of interpreting the complex features they learn. Several models of how combinatorial b...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Chen, Ling, Capra, John A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660921/
https://ncbi.nlm.nih.gov/pubmed/33137083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008334
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