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Learning and interpreting the gene regulatory grammar in a deep learning framework

Deep neural networks (DNNs) have achieved state-of-the-art performance in identifying gene regulatory sequences, but they have provided limited insight into the biology of regulatory elements due to the difficulty of interpreting the complex features they learn. Several models of how combinatorial b...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Chen, Ling, Capra, John A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660921/
https://ncbi.nlm.nih.gov/pubmed/33137083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008334
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