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Learning and interpreting the gene regulatory grammar in a deep learning framework

Deep neural networks (DNNs) have achieved state-of-the-art performance in identifying gene regulatory sequences, but they have provided limited insight into the biology of regulatory elements due to the difficulty of interpreting the complex features they learn. Several models of how combinatorial b...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Chen, Ling, Capra, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660921/
https://ncbi.nlm.nih.gov/pubmed/33137083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008334
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