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Abnormal NFAT5 Physiology in Duchenne Muscular Dystrophy Fibroblasts as a Putative Explanation for the Permanent Fibrosis Formation in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is characterized by chronic inflammation and fibrotic tissue production by fibroblasts. The promyogenic factor nuclear factor of activated T-cells 5 (NFAT5) is virtually present in all cells, responding to hyperosmolar or pro-inflammatory stress. In embryogenic fibr...

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Foilsithe in:Int J Mol Sci
Main Authors: Herbelet, Sandrine, De Paepe, Boel, De Bleecker, Jan L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660673/
https://ncbi.nlm.nih.gov/pubmed/33114289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217888
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