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Abnormal NFAT5 Physiology in Duchenne Muscular Dystrophy Fibroblasts as a Putative Explanation for the Permanent Fibrosis Formation in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is characterized by chronic inflammation and fibrotic tissue production by fibroblasts. The promyogenic factor nuclear factor of activated T-cells 5 (NFAT5) is virtually present in all cells, responding to hyperosmolar or pro-inflammatory stress. In embryogenic fibr...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Herbelet, Sandrine, De Paepe, Boel, De Bleecker, Jan L.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660673/
https://ncbi.nlm.nih.gov/pubmed/33114289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217888
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