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Anti-Inflammatory and General Glucocorticoid Physiology in Skeletal Muscles Affected by Duchenne Muscular Dystrophy: Exploration of Steroid-Sparing Agents

In Duchenne muscular dystrophy (DMD), the activation of proinflammatory and metabolic cellular pathways in skeletal muscle cells is an inherent characteristic. Synthetic glucocorticoid intake counteracts the majority of these mechanisms. However, glucocorticoids induce burdensome secondary effects,...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Herbelet, Sandrine, Rodenbach, Arthur, De Paepe, Boel, De Bleecker, Jan L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369834/
https://ncbi.nlm.nih.gov/pubmed/32605223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134596
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