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Anti-Inflammatory and General Glucocorticoid Physiology in Skeletal Muscles Affected by Duchenne Muscular Dystrophy: Exploration of Steroid-Sparing Agents

In Duchenne muscular dystrophy (DMD), the activation of proinflammatory and metabolic cellular pathways in skeletal muscle cells is an inherent characteristic. Synthetic glucocorticoid intake counteracts the majority of these mechanisms. However, glucocorticoids induce burdensome secondary effects,...

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Pubblicato in:Int J Mol Sci
Autori principali: Herbelet, Sandrine, Rodenbach, Arthur, De Paepe, Boel, De Bleecker, Jan L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369834/
https://ncbi.nlm.nih.gov/pubmed/32605223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134596
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