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From Suppressor T Cells to Regulatory T Cells: How the Journey that Began with the Discovery of the Toxic Effects of TCDD Led to Better Understanding of the Role of AhR in Immunoregulation

Aryl hydrocarbon receptor (AhR) was identified in the early 1970s as a receptor for the ubiquitous environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin), which is a member of halogenated aromatic hydrocarbons (HAHs). TCDD was found to be highly toxic to the immune system, caus...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Prasad Singh, Narendra, Nagarkatti, Mitzi, Nagarkatti, Prakash
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660163/
https://ncbi.nlm.nih.gov/pubmed/33105907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217849
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