AhR Activation by TCDD (2,3,7,8-Tetrachlorodibenzo-p-dioxin) Attenuates Pertussis Toxin-Induced Inflammatory Responses by Differential Regulation of Tregs and Th17 Cells Through Specific Targeting by microRNA

The Aryl Hydrocarbon Receptor (AhR) is a transcription factor that, when activated by ligand-binding, has been shown to regulate the immune response. Pertussis Toxin (PTX) is a virulence factor found in Bordetella pertussis, a human respiratory pathogen that causes whooping cough. PTX promotes colon...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Al-Ghezi, Zinah Zamil, Singh, Narendra, Mehrpouya-Bahrami, Pegah, Busbee, Philip Brandon, Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813193/
https://ncbi.nlm.nih.gov/pubmed/31681214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02349
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