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From Suppressor T Cells to Regulatory T Cells: How the Journey that Began with the Discovery of the Toxic Effects of TCDD Led to Better Understanding of the Role of AhR in Immunoregulation

Aryl hydrocarbon receptor (AhR) was identified in the early 1970s as a receptor for the ubiquitous environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin), which is a member of halogenated aromatic hydrocarbons (HAHs). TCDD was found to be highly toxic to the immune system, caus...

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Pubblicato in:Int J Mol Sci
Autori principali: Prasad Singh, Narendra, Nagarkatti, Mitzi, Nagarkatti, Prakash
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660163/
https://ncbi.nlm.nih.gov/pubmed/33105907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217849
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