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From Suppressor T Cells to Regulatory T Cells: How the Journey that Began with the Discovery of the Toxic Effects of TCDD Led to Better Understanding of the Role of AhR in Immunoregulation

Aryl hydrocarbon receptor (AhR) was identified in the early 1970s as a receptor for the ubiquitous environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin), which is a member of halogenated aromatic hydrocarbons (HAHs). TCDD was found to be highly toxic to the immune system, caus...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Prasad Singh, Narendra, Nagarkatti, Mitzi, Nagarkatti, Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660163/
https://ncbi.nlm.nih.gov/pubmed/33105907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217849
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