FIT2 is an acyl–coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis

The endoplasmic reticulum is a cellular hub of lipid metabolism, coordinating lipid synthesis with continuous changes in metabolic flux. Maintaining ER lipid homeostasis despite these fluctuations is crucial to cell function and viability. Here, we identify a novel mechanism that is crucial for norm...

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Vydáno v:J Cell Biol
Hlavní autoři: Becuwe, Michel, Bond, Laura M., Pinto, Antonio F.M., Boland, Sebastian, Mejhert, Niklas, Elliott, Shane D., Cicconet, Marcelo, Graham, Morven M., Liu, Xinran N., Ilkayeva, Olga, Saghatelian, Alan, Walther, Tobias C., Farese, Robert V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659722/
https://ncbi.nlm.nih.gov/pubmed/32915949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006111
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