FIT2 is an acyl–coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis

The endoplasmic reticulum is a cellular hub of lipid metabolism, coordinating lipid synthesis with continuous changes in metabolic flux. Maintaining ER lipid homeostasis despite these fluctuations is crucial to cell function and viability. Here, we identify a novel mechanism that is crucial for norm...

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Pubblicato in:J Cell Biol
Autori principali: Becuwe, Michel, Bond, Laura M., Pinto, Antonio F.M., Boland, Sebastian, Mejhert, Niklas, Elliott, Shane D., Cicconet, Marcelo, Graham, Morven M., Liu, Xinran N., Ilkayeva, Olga, Saghatelian, Alan, Walther, Tobias C., Farese, Robert V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659722/
https://ncbi.nlm.nih.gov/pubmed/32915949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006111
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