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Bach1‐mediated suppression of p53 is inhibited by p19(ARF) independently of MDM2
Cellular senescence prevents the aberrant proliferation of damaged cells. The transcription factor Bach1 binds to p53 to repress cellular senescence, but it is still unclear how the Bach1–p53 interaction is regulated. We found that the Bach1–p53 interaction was inhibited by oncogenic Ras, bleomycin,...
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| Publié dans: | Cancer Sci |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7659397/ https://ncbi.nlm.nih.gov/pubmed/22348305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02244.x |
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