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Chemical synthesis of human milk oligosaccharides: lacto-N-neohexaose (Galβ1 → 4GlcNAcβ1→)(2) 3,6Galβ1 → 4Glc
The first chemical synthesis of lacto-N-neohexaose (LNnH) has been completed using a convergent synthetic strategy. The reaction conditions and donor–acceptor combinations have been carefully refined to minimize side reactions and achieve high yields in all glycosylation steps. Lacto-N-neotetraose,...
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| Published in: | Org Biomol Chem |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7658587/ https://ncbi.nlm.nih.gov/pubmed/32048706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ob00172d |
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