The Dunkin Hartley Guinea Pig Is a Model of Primary Osteoarthritis That Also Exhibits Early Onset Myofiber Remodeling That Resembles Human Musculoskeletal Aging

Skeletal muscle dysfunction, articular cartilage degeneration, and bone loss occur essentially in parallel during aging. Mechanisms contributing to this systemic musculoskeletal decline remain incompletely understood, limiting progress toward developing effective therapeutics. Because the progressio...

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Publicat a:Front Physiol
Autors principals: Musci, Robert V., Walsh, Maureen A., Konopka, Adam R., Wolff, Christopher A., Peelor, Frederick F., Reiser, Raoul F., Santangelo, Kelly S., Hamilton, Karyn L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658338/
https://ncbi.nlm.nih.gov/pubmed/33192568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.571372
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