The Dunkin Hartley Guinea Pig Is a Model of Primary Osteoarthritis That Also Exhibits Early Onset Myofiber Remodeling That Resembles Human Musculoskeletal Aging

Skeletal muscle dysfunction, articular cartilage degeneration, and bone loss occur essentially in parallel during aging. Mechanisms contributing to this systemic musculoskeletal decline remain incompletely understood, limiting progress toward developing effective therapeutics. Because the progressio...

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Pubblicato in:Front Physiol
Autori principali: Musci, Robert V., Walsh, Maureen A., Konopka, Adam R., Wolff, Christopher A., Peelor, Frederick F., Reiser, Raoul F., Santangelo, Kelly S., Hamilton, Karyn L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658338/
https://ncbi.nlm.nih.gov/pubmed/33192568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.571372
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