The Dunkin Hartley Guinea Pig Is a Model of Primary Osteoarthritis That Also Exhibits Early Onset Myofiber Remodeling That Resembles Human Musculoskeletal Aging

Skeletal muscle dysfunction, articular cartilage degeneration, and bone loss occur essentially in parallel during aging. Mechanisms contributing to this systemic musculoskeletal decline remain incompletely understood, limiting progress toward developing effective therapeutics. Because the progressio...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Musci, Robert V., Walsh, Maureen A., Konopka, Adam R., Wolff, Christopher A., Peelor, Frederick F., Reiser, Raoul F., Santangelo, Kelly S., Hamilton, Karyn L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658338/
https://ncbi.nlm.nih.gov/pubmed/33192568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.571372
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