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Characterization of Bone Perfusion by Dynamic Contrast-Enhanced Magnetic Resonance Imaging and Positron Emission Tomography in the Dunkin-Hartley Guinea Pig Model of Advanced Osteoarthritis

PURPOSE: This study characterizes changes in subchondral bone circulation in OA and examines relationships to bone structure and cartilage degeneration in Dunkin-Hartley guinea pigs. METHODS: We have used dynamic contrast-enhanced MRI (DCE-MRI) and PET, with pharmacokinetic modeling, to characterize...

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發表在:J Orthop Res
Main Authors: Dyke, Jonathan P., Synan, Michael, Ezell, Paula, Ballon, Douglas, Racine, Jennifer, Aaron, Roy K.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346481/
https://ncbi.nlm.nih.gov/pubmed/25410523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22768
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