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Characterization of Bone Perfusion by Dynamic Contrast-Enhanced Magnetic Resonance Imaging and Positron Emission Tomography in the Dunkin-Hartley Guinea Pig Model of Advanced Osteoarthritis
PURPOSE: This study characterizes changes in subchondral bone circulation in OA and examines relationships to bone structure and cartilage degeneration in Dunkin-Hartley guinea pigs. METHODS: We have used dynamic contrast-enhanced MRI (DCE-MRI) and PET, with pharmacokinetic modeling, to characterize...
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Publicado no: | J Orthop Res |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4346481/ https://ncbi.nlm.nih.gov/pubmed/25410523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22768 |
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