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Tumor-targeted delivery of siRNA to silence Sox2 gene expression enhances therapeutic response in hepatocellular carcinoma

RNA interference (RNAi) is one of the most promising methods for the treatment of malignant tumors. However, developing an efficient biocompatible delivery vector for small interfering RNA (siRNA) remains a challenging issue. This study aimed to prepare a non-viral tumor-targeted carrier, named RGDf...

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Detalhes bibliográficos
Publicado no:Bioact Mater
Main Authors: Xia, Yu, Tang, Guoyi, Chen, Yi, Wang, Changbing, Guo, Min, Xu, Tiantian, Zhao, Mingqi, Zhou, Yongjian
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658325/
https://ncbi.nlm.nih.gov/pubmed/33210026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioactmat.2020.10.019
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