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siRNA-loaded selenium nanoparticle modified with hyaluronic acid for enhanced hepatocellular carcinoma therapy

BACKGROUND: Small interfering RNA (siRNA) as a new therapeutic modality holds promise for cancer treatment. However, the traditional viral carriers are prone to immunogenicity and risk of insertional mutagenesis. METHODS: In order to provide a tumor-targeted delivery carrier of siRNA in cancer thera...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Xia, Yu, Guo, Min, Xu, Tiantian, Li, Yinghua, Wang, Changbing, Lin, Zhengfang, Zhao, Mingqi, Zhu, Bing
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858822/
https://ncbi.nlm.nih.gov/pubmed/29588583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S157519
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