Tumor-targeted delivery of siRNA to silence Sox2 gene expression enhances therapeutic response in hepatocellular carcinoma

RNA interference (RNAi) is one of the most promising methods for the treatment of malignant tumors. However, developing an efficient biocompatible delivery vector for small interfering RNA (siRNA) remains a challenging issue. This study aimed to prepare a non-viral tumor-targeted carrier, named RGDf...

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Bibliografiske detaljer
Udgivet i:Bioact Mater
Main Authors: Xia, Yu, Tang, Guoyi, Chen, Yi, Wang, Changbing, Guo, Min, Xu, Tiantian, Zhao, Mingqi, Zhou, Yongjian
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Publishing 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658325/
https://ncbi.nlm.nih.gov/pubmed/33210026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioactmat.2020.10.019
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