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Tissue-specific Nrf2 signaling protects against methylmercury toxicity in Drosophila neuromuscular development.

Methylmercury (MeHg) can elicit cognitive and motor deficits due to its developmental neuro- and myotoxic properties. While previous work has demonstrated that Nrf2 antioxidant signaling protects from MeHg toxicity, in vivo tissue-specific studies are lacking. In Drosophila, MeHg exposure shows grea...

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Bibliografische gegevens
Gepubliceerd in:Arch Toxicol
Hoofdauteurs: Gunderson, Jakob, Peppriell, Ashley, Vorojeikina, Daria, Rand, Matthew D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657992/
https://ncbi.nlm.nih.gov/pubmed/32816092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02879-z
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