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Tissue-specific Nrf2 signaling protects against methylmercury toxicity in Drosophila neuromuscular development.

Methylmercury (MeHg) can elicit cognitive and motor deficits due to its developmental neuro- and myotoxic properties. While previous work has demonstrated that Nrf2 antioxidant signaling protects from MeHg toxicity, in vivo tissue-specific studies are lacking. In Drosophila, MeHg exposure shows grea...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Gunderson, Jakob, Peppriell, Ashley, Vorojeikina, Daria, Rand, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657992/
https://ncbi.nlm.nih.gov/pubmed/32816092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02879-z
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