Editor's Highlight: Glutathione S-Transferase Activity Moderates Methylmercury Toxicity During Development in Drosophila

Glutathione (GSH) pathways play a central role in methylmercury (MeHg) metabolism and elimination, largely due to formation of a more readily transported MeHg-GSH conjugate. Glutathione S-transferases (GSTs) have therefore been proposed to facilitate MeHg elimination by catalyzing MeHg-GSH conjugati...

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Détails bibliographiques
Publié dans:Toxicol Sci
Auteurs principaux: Vorojeikina, Daria, Broberg, Karin, Love, Tanzy M., Davidson, Philip W., van Wijngaarden, Edwin, Rand, Matthew D.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Glutathione S-Transferase in Methylmercury Toxicity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837650/
https://ncbi.nlm.nih.gov/pubmed/28184905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx033
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