Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders

Substantial genetic liability is shared across psychiatric disorders but less is known about risk variants that are specific to a given disorder. We used multi-trait conditional and joint analysis (mtCOJO) to adjust GWAS summary statistics of one disorder for the effects of genetically correlated tr...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Psychiatry
मुख्य लेखकों: Byrne, Enda M, Zhu, Zhihong, Qi, Ting, Skene, Nathan G, Bryois, Julien, Pardinas, Antonio F, Stahl, Eli, Smoller, Jordan W, Rietschel, Marcella, Owen, Michael J, Walters, James T.R., O’Donovan, Michael C, McGrath, John G, Hjerling-Leffler, Jens, Sullivan, Patrick F, Goddard, Michael E, Visscher, Peter M, Yang, Jian, Wray, Naomi R
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657979/
https://ncbi.nlm.nih.gov/pubmed/32398722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-020-0705-9
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