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Causal associations between risk factors and common diseases inferred from GWAS summary data

Health risk factors such as body mass index (BMI) and serum cholesterol are associated with many common diseases. It often remains unclear whether the risk factors are cause or consequence of disease, or whether the associations are the result of confounding. We develop and apply a method (called GS...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Zhu, Zhihong, Zheng, Zhili, Zhang, Futao, Wu, Yang, Trzaskowski, Maciej, Maier, Robert, Robinson, Matthew R., McGrath, John J., Visscher, Peter M., Wray, Naomi R., Yang, Jian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768719/
https://ncbi.nlm.nih.gov/pubmed/29335400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02317-2
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